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Forum Home > General Discussion > Tylosin every 3 months?

Luna (GSD) and Kandi
Member
Posts: 11

Hi - my luna girl seems to have "flair ups" about every 3 months after using the tylosin for 3 months.  Does anyone have any advise about possibly going on a maintenance dose of tylosin?  My vet basically said to mark my calendar for 2 1/2 months and put her on the tylosin again

Thanks!

--
May 6, 2018 at 7:08 PM Flag Quote & Reply

maddie ann
Administrator
Posts: 3678

Hello we suggest that you taper the tylan dose down gradually rather than just stop it after 45 days...what dose was Luna on and how much does she weigh were you also giving it twice a day with food ? 

--

 ANN (UK).

Maddie DOB 01-10-2007 she is now  10  DX 04/11 .B12 140 now 644 TLI <1.00 Folate 14.2.

After 15 months on the B12 tablets with the intrisic factor she was retested and her b12 was 902 which gave me the confidence to continue without injections.

Weight was 22.3kg now 33.2kg (04-05-12) she is a small GSDbut she gained .(24lbs)

Feed a mixture of foods she does better on fibre 3% and below she has  b12 tablets daily (imported from the USAhttp://www.wonderlabs.com/itemleft.php?itemnum=6881) now changing to the uk version from http://www.chemeyes.co.uk/

She has panzym altough over the years we have had to increase the dose she currently has 1/2 tsp per feed.


May 7, 2018 at 6:33 AM Flag Quote & Reply

Luna (GSD) and Kandi
Member
Posts: 11

Great questions!

Luna is 77 lbs and was given Tylosin 800 twice a day with food

For tapering - does that mean half the dose?

Thanks you so much!

May 7, 2018 at 10:48 AM Flag Quote & Reply

Riley's Mom
Administrator
Posts: 2001

A slow way to wean would be:

half the dose 2x per day for a week, then half again 2x per day for a week, then that same dose once a day for a week, then once per day every other day for a week then stop. All the while watch Luna's response to see if the poops are staying good. And keep watching at your "danger" zone time of 3 months to see if anything crops back up.

Let us know how it goes!

--

Elisabeth

Riley's Mom from Chesapeake, VA

Riley, 8 yr old Labradoodle diagnosed September 2014 cTLI 1.6

Weight before diagnosis 40 lbs, lowest weight 33 lbs, ready for the Chunky Monkey club as she weighed in at a whopping 42 pounds on 12/19/14!

Update: as of 2/25/15 Riley weighs in at 44.2 pounds!

Update: as of 6/15/15 Riley weighs in at 45 pounds!

Feeding grain free kibble TOTW, 1 tsp of Diane's 6x enzymes per cup of food. (I mix the enzymes in something moist). She is a picky eater--lately feeding her on a flat plate is the way to entice her to eat. 1 cup in the am, 2 cups in the pm, 1 tsp of coconut oil per meal, 1 packet of FortiFlora probiotic in the pm meal.

Began weekly B12 shots 10/23/14. Holding on shots for now.

Began 1 Wonderlabs B12 in the morning, 1 in the evening. Capsule opened up and sprinkled on her food.


*I am not a vet, anything I share or suggest on this site is solely from my experience as an EPI dog owner. It is recommended that anything shared or suggested on this forum be discussed with your pet's vet.*

May 7, 2018 at 11:01 AM Flag Quote & Reply

Barb
Administrator
Posts: 3955

Hello.  Lis's tapering off schedule is excellent.  Just remember that every dog is different, so keep a daily journal.  When we tried to take Kolby off, we would get all the way to stopping and everything would be fine for about 10 days. to almost two weeks.....but we could never get past the two week tylosin- free-mark without .his poos going south.  We finally accepted that he had to be on maintenance.  


This is not to say that Luna will have these issues.  She may respond well to tapering off slowly.  But don't be discouraged if she needs maintenance.


Let us know how she does.


Barb  

--


May 7, 2018 at 11:53 AM Flag Quote & Reply

Doc's Mom
Administrator
Posts: 3150

The weaning off schedule above is great. It's odd that it happens every 3 months.  Is there anything in her routine that changes every 3 months - like flea/tick meds or something?

--

MADELON and DOC aka "BUBBY WUBBY"

Nashville, Tennessee

DOB: 4/3/2014 - Diagnosed EPI and SIBO: 5/22/2015
EPI Test Results: 1st test 7/2014 = TLI 16.5, B12 894, Folate > 24; 
2nd test 5/2015 = TLI < .4, B12 406; Folate >24; 3rd test 10/2015   TLI < .4; B12 >1000; Folate 14.4

Weight: 95 (highest 1/2015) - 76 (lowest 5/2015) - goal met 100lb (7/23/15) - 101.8LBS 12/3/15 - CHUNKY MONKEY

History prior to DX:  May/June 2014 (2mos old) - DX coccidia and bladder infection; July 2014 (3mos old) 1st EPI test = TLI 16.5, B12 894, Folate >24 - Diagnosed SIBO not EPI; Feb 2015 thru May 2015 - weight loss only; May  2015 vomitted several times, diarrhea and eating poop.

History since DX: has maintained weight between 95-101lbs since July 2015; extreme yeast and rod infection in ears; yeast infection paws (ongoing); bacterial eye infection; bacterial skin infection on legs; poops LIVE fly larvae; diagnosed with mild, focal superficial pyoderma (bacterial infection) - rare lesions on inner thighs; bacterial and yeast overgrowth lip folds; yeast overgrowth feet and left ear; metacarpal/metatarsal draining tracts/fistulae (infection and/or immune mediated disease; probable underlying allergy (food vs. environmental ); staphylococcus pseudintermedius infection in sores on paws; recurring metatarsal fistula - all issues resolved after NutriScan Food Sensitivity Test and switching foods.

NUTRISCAN Food Sensitivity Test (12/2015): reactive to chicken, turkey, white fish, wheat, white potato (mild), venison, soy (mild), pork (mild), duck (mild), corn - switching food based on test resolved all skin issues.

Serum Allergy Test (5/2016): Too many to mention

CURRENTLY :  6 cups Forza10 Legend Skin - Diane 6x 1tsp per cup; 1 WonderLab PetFactor B12 2x day; 2 scoops TotalBiotics 1x day; 600mg vitamin E; 1 Zyrtec 10mg 2x day; Milk Thistle during heartworm/flea/tick meds

I am not a vet.  All of my suggestions are based on my personal experiences, information gleaned from EPI research and information from other EPI owners.  Please always share anything and everything recommended on this forum with your vet

SO THANKfUL FOR OUR EPI4DOGS GUARDIAN ANGELS!!!!!!!!

YOUR PAWS LEFT PRINTS ON MY HEART (in loving memory of Bugsy aka Boo Boo - Boston Terrier 14yrs - not EPI but medically challenging and totally worth it)


May 7, 2018 at 1:10 PM Flag Quote & Reply

Luna (GSD) and Kandi
Member
Posts: 11

Thank you Riley's mom!  A new experiment begins!! :)

May 7, 2018 at 7:11 PM Flag Quote & Reply

maddie ann
Administrator
Posts: 3678

Good luck let us know how you get on ...i assume Luna has B12 as well.

--

 ANN (UK).

Maddie DOB 01-10-2007 she is now  10  DX 04/11 .B12 140 now 644 TLI <1.00 Folate 14.2.

After 15 months on the B12 tablets with the intrisic factor she was retested and her b12 was 902 which gave me the confidence to continue without injections.

Weight was 22.3kg now 33.2kg (04-05-12) she is a small GSDbut she gained .(24lbs)

Feed a mixture of foods she does better on fibre 3% and below she has  b12 tablets daily (imported from the USAhttp://www.wonderlabs.com/itemleft.php?itemnum=6881) now changing to the uk version from http://www.chemeyes.co.uk/

She has panzym altough over the years we have had to increase the dose she currently has 1/2 tsp per feed.


May 8, 2018 at 4:56 AM Flag Quote & Reply

Paige's Guardian
Member
Posts: 104

Probiotics.  I think Olesia shared a study where they tried each Tylosin in one group and Probiotic in another.  The group on Probiotics has less relapses.  Check the SIBO tab and I think the information is there....

Maybe get her on a Probiotic??  I use ProviableDC (Amazon) has the best price. 

May 8, 2018 at 7:07 AM Flag Quote & Reply

Luna (GSD) and Kandi
Member
Posts: 11

Doc's Mom at May 7, 2018 at 1:10 PM

The weaning off schedule above is great. It's odd that it happens every 3 months.  Is there anything in her routine that changes every 3 months - like flea/tick meds or something?

I can't find anything that changes for her.  She stays on the same meds and I am lucky to not need any flea / tick meds.  This is one of the reasons it's frusterating!!

May 8, 2018 at 1:04 PM Flag Quote & Reply

Luna (GSD) and Kandi
Member
Posts: 11

Barb at May 7, 2018 at 11:53 AM

Hello.  Lis's tapering off schedule is excellent.  Just remember that every dog is different, so keep a daily journal.  When we tried to take Kolby off, we would get all the way to stopping and everything would be fine for about 10 days. to almost two weeks.....but we could never get past the two week tylosin- free-mark without .his poos going south.  We finally accepted that he had to be on maintenance.  


This is not to say that Luna will have these issues.  She may respond well to tapering off slowly.  But don't be discouraged if she needs maintenance.


Let us know how she does.


Barb  

Thanks Barb.  I know it will be an experiment for sure!!

May 8, 2018 at 1:05 PM Flag Quote & Reply

Luna (GSD) and Kandi
Member
Posts: 11

maddie ann at May 8, 2018 at 4:56 AM

Good luck let us know how you get on ...i assume Luna has B12 as well.

yes, she is on weekly B12 shots. 

May 8, 2018 at 1:06 PM Flag Quote & Reply

Luna (GSD) and Kandi
Member
Posts: 11

Paige's Guardian at May 8, 2018 at 7:07 AM

Probiotics.  I think Olesia shared a study where they tried each Tylosin in one group and Probiotic in another.  The group on Probiotics has less relapses.  Check the SIBO tab and I think the information is there....

Maybe get her on a Probiotic??  I use ProviableDC (Amazon) has the best price. 

She is on probiotics.  

May 8, 2018 at 1:07 PM Flag Quote & Reply

Doc's Mom
Administrator
Posts: 3150

The study Paige's Guardian is referring to was using a Prebiotic - Slippery Elm Bark Powder, which we have seen great results with.

--

MADELON and DOC aka "BUBBY WUBBY"

Nashville, Tennessee

DOB: 4/3/2014 - Diagnosed EPI and SIBO: 5/22/2015
EPI Test Results: 1st test 7/2014 = TLI 16.5, B12 894, Folate > 24; 
2nd test 5/2015 = TLI < .4, B12 406; Folate >24; 3rd test 10/2015   TLI < .4; B12 >1000; Folate 14.4

Weight: 95 (highest 1/2015) - 76 (lowest 5/2015) - goal met 100lb (7/23/15) - 101.8LBS 12/3/15 - CHUNKY MONKEY

History prior to DX:  May/June 2014 (2mos old) - DX coccidia and bladder infection; July 2014 (3mos old) 1st EPI test = TLI 16.5, B12 894, Folate >24 - Diagnosed SIBO not EPI; Feb 2015 thru May 2015 - weight loss only; May  2015 vomitted several times, diarrhea and eating poop.

History since DX: has maintained weight between 95-101lbs since July 2015; extreme yeast and rod infection in ears; yeast infection paws (ongoing); bacterial eye infection; bacterial skin infection on legs; poops LIVE fly larvae; diagnosed with mild, focal superficial pyoderma (bacterial infection) - rare lesions on inner thighs; bacterial and yeast overgrowth lip folds; yeast overgrowth feet and left ear; metacarpal/metatarsal draining tracts/fistulae (infection and/or immune mediated disease; probable underlying allergy (food vs. environmental ); staphylococcus pseudintermedius infection in sores on paws; recurring metatarsal fistula - all issues resolved after NutriScan Food Sensitivity Test and switching foods.

NUTRISCAN Food Sensitivity Test (12/2015): reactive to chicken, turkey, white fish, wheat, white potato (mild), venison, soy (mild), pork (mild), duck (mild), corn - switching food based on test resolved all skin issues.

Serum Allergy Test (5/2016): Too many to mention

CURRENTLY :  6 cups Forza10 Legend Skin - Diane 6x 1tsp per cup; 1 WonderLab PetFactor B12 2x day; 2 scoops TotalBiotics 1x day; 600mg vitamin E; 1 Zyrtec 10mg 2x day; Milk Thistle during heartworm/flea/tick meds

I am not a vet.  All of my suggestions are based on my personal experiences, information gleaned from EPI research and information from other EPI owners.  Please always share anything and everything recommended on this forum with your vet

SO THANKfUL FOR OUR EPI4DOGS GUARDIAN ANGELS!!!!!!!!

YOUR PAWS LEFT PRINTS ON MY HEART (in loving memory of Bugsy aka Boo Boo - Boston Terrier 14yrs - not EPI but medically challenging and totally worth it)


May 8, 2018 at 1:51 PM Flag Quote & Reply

Luna (GSD) and Kandi
Member
Posts: 11

Doc's Mom at May 8, 2018 at 1:51 PM

The study Paige's Guardian is referring to was using a Prebiotic - Slippery Elm Bark Powder, which we have seen great results with.

oh, ok!  I'll check that out - she is on a prebiotic - inulin, but will look into the slippery Elm...I assume I would need to ween her off of the inulin while introducing the slippery elm powder...any suggestions on how to do that?

Thanks!!!

May 9, 2018 at 2:03 PM Flag Quote & Reply

maddie ann
Administrator
Posts: 3678

Hello when do you give the inulin is it at the same time as the tylan? the reason i ask is that a pre/probotic should not be given at the same time as Tylan as it can stop the effectiveness of the antiboitc.I have used slippery Elm and just swopped over stright away from another pre/pro...again we dont advise giving SE and Tylan togther alot of people have manged with just slippery elm and no tylan .

--

 ANN (UK).

Maddie DOB 01-10-2007 she is now  10  DX 04/11 .B12 140 now 644 TLI <1.00 Folate 14.2.

After 15 months on the B12 tablets with the intrisic factor she was retested and her b12 was 902 which gave me the confidence to continue without injections.

Weight was 22.3kg now 33.2kg (04-05-12) she is a small GSDbut she gained .(24lbs)

Feed a mixture of foods she does better on fibre 3% and below she has  b12 tablets daily (imported from the USAhttp://www.wonderlabs.com/itemleft.php?itemnum=6881) now changing to the uk version from http://www.chemeyes.co.uk/

She has panzym altough over the years we have had to increase the dose she currently has 1/2 tsp per feed.


May 10, 2018 at 5:37 AM Flag Quote & Reply

Luna (GSD) and Kandi
Member
Posts: 11

maddie ann at May 10, 2018 at 5:37 AM

Hello when do you give the inulin is it at the same time as the tylan? the reason i ask is that a pre/probotic should not be given at the same time as Tylan as it can stop the effectiveness of the antiboitc.I have used slippery Elm and just swopped over stright away from another pre/pro...again we dont advise giving SE and Tylan togther alot of people have manged with just slippery elm and no tylan .

Oh My Gosh!!!  I do give it at the same time!!  What is the suggested timeframe to wait between the tylosin and the pre / probiotic?  Where do you get the slippery elm?  Is it a tablet that I could easily pop into her mouth?


Thank you!!!!

May 10, 2018 at 11:03 AM Flag Quote & Reply

Doc's Mom
Administrator
Posts: 3150

We recommend waiting at least 2 hours between antibiotic and probiotic.  A lot of us use the NOW brand of Slippery Elm and you can order it from Amazon.  It's a powder that you mix with about 2Tablespoons of water and then put directly on the food - no need to incubate (dosing information is under the EPI/SID tab above - scroll down to near the bottom of the page)

--

MADELON and DOC aka "BUBBY WUBBY"

Nashville, Tennessee

DOB: 4/3/2014 - Diagnosed EPI and SIBO: 5/22/2015
EPI Test Results: 1st test 7/2014 = TLI 16.5, B12 894, Folate > 24; 
2nd test 5/2015 = TLI < .4, B12 406; Folate >24; 3rd test 10/2015   TLI < .4; B12 >1000; Folate 14.4

Weight: 95 (highest 1/2015) - 76 (lowest 5/2015) - goal met 100lb (7/23/15) - 101.8LBS 12/3/15 - CHUNKY MONKEY

History prior to DX:  May/June 2014 (2mos old) - DX coccidia and bladder infection; July 2014 (3mos old) 1st EPI test = TLI 16.5, B12 894, Folate >24 - Diagnosed SIBO not EPI; Feb 2015 thru May 2015 - weight loss only; May  2015 vomitted several times, diarrhea and eating poop.

History since DX: has maintained weight between 95-101lbs since July 2015; extreme yeast and rod infection in ears; yeast infection paws (ongoing); bacterial eye infection; bacterial skin infection on legs; poops LIVE fly larvae; diagnosed with mild, focal superficial pyoderma (bacterial infection) - rare lesions on inner thighs; bacterial and yeast overgrowth lip folds; yeast overgrowth feet and left ear; metacarpal/metatarsal draining tracts/fistulae (infection and/or immune mediated disease; probable underlying allergy (food vs. environmental ); staphylococcus pseudintermedius infection in sores on paws; recurring metatarsal fistula - all issues resolved after NutriScan Food Sensitivity Test and switching foods.

NUTRISCAN Food Sensitivity Test (12/2015): reactive to chicken, turkey, white fish, wheat, white potato (mild), venison, soy (mild), pork (mild), duck (mild), corn - switching food based on test resolved all skin issues.

Serum Allergy Test (5/2016): Too many to mention

CURRENTLY :  6 cups Forza10 Legend Skin - Diane 6x 1tsp per cup; 1 WonderLab PetFactor B12 2x day; 2 scoops TotalBiotics 1x day; 600mg vitamin E; 1 Zyrtec 10mg 2x day; Milk Thistle during heartworm/flea/tick meds

I am not a vet.  All of my suggestions are based on my personal experiences, information gleaned from EPI research and information from other EPI owners.  Please always share anything and everything recommended on this forum with your vet

SO THANKfUL FOR OUR EPI4DOGS GUARDIAN ANGELS!!!!!!!!

YOUR PAWS LEFT PRINTS ON MY HEART (in loving memory of Bugsy aka Boo Boo - Boston Terrier 14yrs - not EPI but medically challenging and totally worth it)


May 10, 2018 at 12:41 PM Flag Quote & Reply

Luna (GSD) and Kandi
Member
Posts: 11

Doc's Mom at May 10, 2018 at 12:41 PM

We recommend waiting at least 2 hours between antibiotic and probiotic.  A lot of us use the NOW brand of Slippery Elm and you can order it from Amazon.  It's a powder that you mix with about 2Tablespoons of water and then put directly on the food - no need to incubate (dosing information is under the EPI/SID tab above - scroll down to near the bottom of the page)

Great - thank you for bearing with me!  My next question is - how do I give the Tylosin to her after 2 hours since it's a powder?


Thankyou much!!!!!

May 10, 2018 at 3:18 PM Flag Quote & Reply

Jill
Administrator
Posts: 3728
The tylosin is bitter. Some dogs don't mind the taste in their food but alot of folks put the doses in gel capsules.
--

   Jill-  Washington State

Mickey 6/21/99 - 8/29/2014 

17.5 lb  jack russell, chronic pancreatitis, hyperuricosuria,high blood pressure, hypothyroid, spinal stenosis

diet of  hard boiled eggs, macaroni,  RC Hepatic, mashed potato

2 #2 Dianes enzymes 6x premeal

 2.5 mg Amlodipine, .15mg soloxine am/pm, 100mg ursodiol started for gall bladder thinning

arthritis:  6.25mg tramadol 1x/day, 12.5mg gabapentin every 12 hrs,  Assisi soft loop used on back and elbow, 1- 540meq potassium citrate nightly

Denamarin once a day, 1/16 t tylan (150mg)  2x/day ,  Senilife started 12/14/13, Trixsyn sirup for arthritis, .1mg Adequan weekly by shot. 75mg Tylan 2x./day for SIBO

Optimmune for Dry eyes

 Kiya is Mickeys sister, 3/4 aussie, 1/4 blue heeler born 9/2006.  She thinks she is a 44 lb jack russell who tries to heel Mickey!!

TJ is the newest addition.  He is in the bottom picture with Kiya.  He was born 7/05/2015. 

I am not a vet, just a pet owner sharing what experiences I have had in helping my dogs with other pet owners.  If you have an emergency please call your vet.





May 10, 2018 at 11:30 PM Flag Quote & Reply

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