EPI * Exocrine Pancreatic Insufficiency

Hi guys

There is nothing on the box or the tub but reading Donna's post it occurred to me whether or not they should be kept in the fridge - they are tryplase capsules??  Anyone know?

I don't know anything about tryplase. I use the powdered enzymes and I do not refrigerate. One of the powdered enzymes says to store in a tightly closed container, temperature should not exceed 35 C (95 F).

some people do refrigerate their enzymes - most don't

found this on tryplase capsules

- Pharmaceutical precautions Store in tightly closed original container in a dry place below 25°C.

HI Rachel,

I have no idea on what you are using, but I know our enzymes (Pancreatin) does deteriorate with heat and we've had several weeks above 95 degrees F and I don't have AC, so thus the reason I store new, unopened enzymes in the fridge.

I have NEVER kept Tryplase in the fridge... just keep it in a cool cupboard and it will be fine.

Val

Thanks guys.  We are in the middle of a heatwave so I wasn't sure but the cupboard is pretty cool as its a stone house with three foot thick walls! Now it will have to be in the fridge then in winter as the hot water pipes run above the cupboard!

Thanks again.

The thing you have to watch with Tryplase in the fridge is that the very LEAST damp WILL melt the green capsules and they will stick like glue to each other.

Even if my hands are a bit damp when I handle the capsules they soften and stick the top to the rest of the capsule and I can't get it open.

Terrible soggy things 

Val

Right oh will keep an eye on it!

"Now it will have to be in the fridge then in winter as the hot water pipes run above the cupboard"

Maybe you could put them in a different cupboard than the one near the water pipes. You know, maybe move around a pig's head or two to free up some space elsewhere....

Actually Kathy, according to Diane, Pancreatin should not be stored over 86 degrees F and not in humidity over 70 percent...As we've had both lately,  I choose to store mine in the fridge...They are simply too expensive to just let sit and lose potency...

From Diane:  http://www.enzymediane.com/commonlyaskedquestions.htm

I keep mine in the fridge and freezer both.  But we don't use tryplase.  Val suggests not using the fridge for those and since she has a stone house, which is cool in the summer, but hot water pipes run above that cupboard in the winter, maybe finding a different cupboard/area is a good idea as Kathy suggested.

I have stored my pancreatin in the fridge when it's really hot - but Laura wants to know how to store Typlase which is a capsule - I have never kept my Creon in the fridge

I was NOT refering to Tryplase, I was refering to Pancreatin "Actually Kathy, according to Diane, Pancreatin should not be stored over 86 degrees F and not in humidity over 70 percent..." There are plenty of folks here reading this thread that DO use Pancreatin.

Is anyone in the US familiar with Dr. Foster and Smith website? We recently got our enzymes there. We got a 12oz container of Pancrezyme from that wesbite for only $129. I believe next time we are going to go with Diane's enzymes after I told my dad I could get a kilo! He insists that we have to store them in the freezer..I told him this probably wasn't a good idea. We now have it out of the freezer because we will be running out of one container of enzymes soon. Will these new enzymes be non-effective?

Donna,

If you read what Kathy said and what she quoted it was about storing tryplase in the winter so I do not see what you keep arguing about has any relevance. If you are going back to Kathy’s earlier post (why?The subject of her last post was obviously about tryplase) she never said to put it in the refrigerator or do not put it in the refrigerator nor did she say put in a cupboard or do not put it in a cupboard. What she said was One of the powdered enzymes says to store in a tightly closed container, temperature should not exceed 35 C (95 F). is word for word what it says on my bottle of PanaKare Plus which is pancreatin. Therefore, your statement about temperature is correct only as far as using Diane’s enzymes, not pancreatin in general. Pancreatin should not be stored over 86degrees F and not in humidity over 70 percent  is incorrect. I will take your word on what the storage requirements are for Diane’s enzymes, made by AmLab, but the requirements for pancreatin from Neogen, another manufacturer, differs. Kathy’s statement is accurate. She said “one” of the powdered enzymes, you said pancreatin.

Ann & Partner-Melrose, MA. USA

I have just read through and you are ALL right about the enzymes.

BUT Tryplase comes in horrible thin green capsules and they melt at the least thing... I wouldn't store them in the fridge even in an airtight container.....

But there is no reason not to give it a try with a few capsules and see how it goes.

Val

I have just looked on the Tryplase tub and the directions are...

Store in a DRY place.. not exceeding 25c.

Duh! Why didn't I think of looking before!

Hi Jessica.  As long as they are stored and enclosed tightly, putting in the freezer should be fine.  When I get mine from Diane, they come in a plastic baggie.  I add a ziploc to that, then put in a ziploc container.  The new batch goes into the freezer.  When out of the freezer, I keep packaged the same, in the fridge, taking out what I need for about a week and store on the counter, away from sunlight, in a jar w/ lid tightly on.  As long as no moisture can hit it, and in a jar tightly sealed, the enzymes should be just fine. I have been doing it this way for a few years and have had no problem.  Hope this helps you some.

I guess the best thing for everyone to do is read the jar/bottle/container etc of their individual enzymes.  Ea may have different directions, storage suggestions, etc.  I think the main thing for all of them is to not let them get too hot nor to get moist.  As long as stored in airtight containers, all should be well, no matter where/how they chose to store.  If worse comes to worse, a person can always call the manufacturer and/or their vet if in doubt.

I've never stored mine in a fridge or freezer - I have a cool dry cupboard where I keep them - in 2 zip lock bags - just my experience...