EPI * Exocrine Pancreatic Insufficiency
managing EPI
Forum
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Site Owner Posts: 10067 |
Just a gentle reminder folks .....Please do not mention specific breeder names on the FORUM. Although i realize everyone's intentions are good ...this could turn into a liability for epi4dogs. You are more than welcome to discuss privately to see who's dog is related to who. The best we can all do is contact our breeder immediately (if there is one) when our dogs are diagnosed to let them know that one of their mating's produced an EPI dog and inform them to the best of our ability about this horrible EPI condition . Other than this, assuming that this or that dog is a carrier is simply an assumption. The genetics are NOT that simple. Often times, a breeding is already done long before the breeder has any indication that there is a possibility of EPI. Until the specific genetics are confirmed (and they are still working on this) .... the researchers are recommending to not breed the same parents to each other (who produced an EPI pup) ... but they can be used for breeding with other mates until further indication. PLEASE read the most recent research study of two confirmed EPI parents and the results of their puppies: http://www.epi4dogs.com/research.htm Brief Communication - J Vet Intern Med 2010;24:450–452 Heritability of Exocrine Pancreatic Insufficiency in German Shepherd Dogs E. Westermarck, S.A.M. Saari, and M.E. Wiberg "Background: Several studies have revealed that exocrine pancreatic insufficiency (EPI) is an inherited disease in German Shepherd Dogs (GSDs). Pedigree analyses have suggested an autosomal recessive inheritance model. Objective: Test mating of 2 dogs with EPI. Animals: A sire and dam purebred GSD both with EPI and a litter of 6 puppies. Methods: Test mating and long-term follow-up of offspring. The pancreas was biopsied via laparotomy on 26 occasions. Serum trypsin-like immunoreactivity was measured. Study was approved by Animal Ethics Committee. Results: During the 12-year study period only 2 of the 6 offsprings developed pancreatic acinar atrophy (PAA). In 1 puppy, end-stage PAA and in the other puppy partial PAA was diagnosed."
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-- Olesia, owned by Izzy-45lb SWD, Diagnosed at 1.5 years old - TLI results 1.3, Stable almost 7 yrs! Once stable, was able to reduce enzymes to only 1/2 tsp of Enzymes with each meal, but after almost 4 years of stabilization... had to increase the amount of enzymes to 3/4 teaspoon with each meal. Feed various grain-free kibble+real meat, 6x pancreatin enzymes from EnzymeDiane. I give 1 tsp of coconut oil one day and 1 tsp salmon oil next day, and also give canned sardines packed without salt or canned herring for extra omega oils.
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Member Posts: 2080 |
Apologies for referring to Maddies kennel club name. I will discuss the relevant relationships with Sky and Ben seven off forum. Ann | |
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-- ANN (UK)
Maddie DOB 01-10-2007 she is now 5 DX 04/11 .B12 140 now 644 TLI <1.00 Folate 14.2. B12 RETESTED 0N 21-05-2013 Value 902 after 15 months of daily piils Yipheeee Weight was 22.3kg now 33.2kg (04-05-12) she is a small GSDbut she gained .(24lbs) Feed a mixture of foods she does better on fibre 3% and below she has b12 tablets daily (imported from the USAhttp://www.wonderlabs.com/itemleft.php?itemnum=6881) now changing to the uk version from http://www.chemeyes.co.uk/ Also omega3 and Vitamin E daily. Use Panzym 1/4 a tsp per 200 grams of food .Got SIBO under control after antibiotics ( stormormgyl) used synbotic by protexin. a pre-probotic
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Site Owner Posts: 10067 |
No problem Ann.... connections are welcomed to be discussed here... such as who's dog may be a cousin, aunt, brother, etc to someone else's dog... just don't mention the actual breeder's name, because if it get's ugly, i can be liable.....and that would be the end of epi4dogs :(. I don't want to make anyone feel bad, afterall....not everyone realizes that this could be an issue.... but since it bubbled up in a topic, i decided now would be a good time to mention not to mention breeder names | |
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-- Olesia, owned by Izzy-45lb SWD, Diagnosed at 1.5 years old - TLI results 1.3, Stable almost 7 yrs! Once stable, was able to reduce enzymes to only 1/2 tsp of Enzymes with each meal, but after almost 4 years of stabilization... had to increase the amount of enzymes to 3/4 teaspoon with each meal. Feed various grain-free kibble+real meat, 6x pancreatin enzymes from EnzymeDiane. I give 1 tsp of coconut oil one day and 1 tsp salmon oil next day, and also give canned sardines packed without salt or canned herring for extra omega oils.
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Member Posts: 1463 |
Thanks for pointing this out Olesia. Perhaps it should be added to the Forum "rules" so it's right there for everyone to be acquainted with?
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- Barb -
Mom to Cedar, diagnosed with EPI Nov 1, 2010, TLI 1.2, Feb 2013 B12 653 (150-700), Folate 23 (7-39); B12 injections weekly; 1 3/4 tsp pancreatin 8X/meal, 1 1/4 c TOTW Pacific Stream or Sierra Mountain + 1/2 c add ins (pork, salmon, sardines, haddock, egg, pumpkin are the usual), 1/3 c water, incubated x 30 minutes; 2 meals/day; current weight 68.9 lbs. Also has Pannus; treated with tacrolimus ointment 2 x daily each eye and gets 100 ug Vit E daily for immature cataracts. Also Mom to pupkids Bree and Griffin, and catkids Abby, Diamond and Max...and skinkid Ayden
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Member Posts: 2080 |
I agree with Barb we need to have it in the rules. Also we need to make it clear that we cant use there KC name here. However i think that it would be useful if off forum we could have the dogs progency so we might be able to collate any links and then put a good case to the relevant breeders i would be quite happy to do this for the UK . Ann.
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-- ANN (UK)
Maddie DOB 01-10-2007 she is now 5 DX 04/11 .B12 140 now 644 TLI <1.00 Folate 14.2. B12 RETESTED 0N 21-05-2013 Value 902 after 15 months of daily piils Yipheeee Weight was 22.3kg now 33.2kg (04-05-12) she is a small GSDbut she gained .(24lbs) Feed a mixture of foods she does better on fibre 3% and below she has b12 tablets daily (imported from the USAhttp://www.wonderlabs.com/itemleft.php?itemnum=6881) now changing to the uk version from http://www.chemeyes.co.uk/ Also omega3 and Vitamin E daily. Use Panzym 1/4 a tsp per 200 grams of food .Got SIBO under control after antibiotics ( stormormgyl) used synbotic by protexin. a pre-probotic
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Member Posts: 826 |
I know they do have this "rule" on the "other" site - they also don't allow you to talk about suppliers of enzymes and other medicines, etc. that EPI dogs might need. That part I don't like because I don't know if I would have found an economical way to manage Sofie's EPI without the advice from this forum. I have taken the subject offline with my breeder and others. Tracey | |
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Site Owner Posts: 10067 |
Great idea.... i will place it in the rules to specifically not to mention breeders by name. However, everyone is still welcome to mention enzymes, food, meds, and if so and so's dog is related to someone else's dog (brother, sister, cousin, aunt etc.) this will not cause any problems. | |
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-- Olesia, owned by Izzy-45lb SWD, Diagnosed at 1.5 years old - TLI results 1.3, Stable almost 7 yrs! Once stable, was able to reduce enzymes to only 1/2 tsp of Enzymes with each meal, but after almost 4 years of stabilization... had to increase the amount of enzymes to 3/4 teaspoon with each meal. Feed various grain-free kibble+real meat, 6x pancreatin enzymes from EnzymeDiane. I give 1 tsp of coconut oil one day and 1 tsp salmon oil next day, and also give canned sardines packed without salt or canned herring for extra omega oils.
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Member Posts: 1463 |
Don't know if you have a legal beagle in the drawer that you could check in with Olesia, but since you're going to amend the Rules to address this, I wonder about also including a statement about not naming vets, rescues, other persons or entities etc in a negative ie potentially libelous context. The risk would be the same as naming a breeder in that context and the rule is intended to mitigate the risk.
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- Barb -
Mom to Cedar, diagnosed with EPI Nov 1, 2010, TLI 1.2, Feb 2013 B12 653 (150-700), Folate 23 (7-39); B12 injections weekly; 1 3/4 tsp pancreatin 8X/meal, 1 1/4 c TOTW Pacific Stream or Sierra Mountain + 1/2 c add ins (pork, salmon, sardines, haddock, egg, pumpkin are the usual), 1/3 c water, incubated x 30 minutes; 2 meals/day; current weight 68.9 lbs. Also has Pannus; treated with tacrolimus ointment 2 x daily each eye and gets 100 ug Vit E daily for immature cataracts. Also Mom to pupkids Bree and Griffin, and catkids Abby, Diamond and Max...and skinkid Ayden
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Member Posts: 826 |
Probably a good idea Barb. | |
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-- Tracey and Sofie Sofie, Shiloh shepherd, born March 2010; diagnosed April 2011. Currently eats 5 cups of Taste of the Wild Sierra Mountain (has no chicken in it) per day plus a bit of cooked beef, pork, tripe or liver, etc. with 1 tsp. of 8x enzymes per cup. 2 Trinfac-B Intrinsic Factor per day. 1/4 tsp. Tylan 2x per day with meals - every time I try to stop the SIBO comes back. Looking at probiotics..
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