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2013 Re-Submision update:
Although Dr. Leigh Anne Clark at Clemson University re-submitted a proposal to The Morris Animal Foundation http://www.morrisanimalfoundation.org/ with regards to a study EPI in Breeds other than the German Shepherd Dog... the proposal was declined
Thank you Dr. Clark http://www.clemsoncaninegenetics.com/ for your continued effort to pursue the genetics of EPI.
There has been a dramatic shift in breeds afflicted with EPI. It previously was predominantly a GSD or a Rough Coated Collie disease. Then it became approximately a 70% GSD disease. Currently 55% of EPI breeds are something other than the GSD! The tide is changing and we desperately need to understand..... why EPI is happening.....what is triggering it....can we do anything to prevent it????
2012 random collection of breeds with EPI
The following data results were used in a preliminary submission by Dr. Leigh Anne Clark at Clemson University for a proposal on
"EPI Research in Breeds Other than the German Shepherd Dog"
as of the November 2012 AKC declined funding for this EPI research
Thank you to EVERYONE who participated. Your data helped support both of these submission!
In an effort to hopefully help the EPI Geneticists, Drs. Leigh Anne Clark and Kate Tsai at Clemson University, secure additional funding needed to further their EPI genetic Research....epi4dogs requested email submissions from EPI owners identifying the breed of their dog. The response was beyond over-whelming!!!! THANK YOU!!
In order to gather truly random results, I purposely did not give the specifics of what the funding was for and simply asked for all breeds, but the stats we needed were to show how many non-GSD breeds are developing EPI.
The results were eye-opening. Just from our random snapshot data, the pool of non-GSD breeds developing EPI are now becoming greater than just the GSD pool.
Based on data collected from two sources only (epi4dogs & EnzymeDiane) we now know of only 11% of AKC - recognized Pure-bred Canine Breeds that have not yet been diagnosed with EPI
The results are as follows (revised 3/23/12) :
In a random snapshot of time (72 hours) we received 509 responses from TLI confirmed EPI owners:
(1) From the general population, only 200 were GSDs = 39% GSDs, 61% were all other breeds(2) From the general population , when the 28 GSD mixed breeds were included with the 200 GSDs = 45% were GSD + GSD mixes but 55% were all other breeds
(3) From the general population, the known 35 non-GSD mixed breeds again surpassed the 28 GSD-mixed breeds by 10%.
| BREEDS | 2012 List A (each mix individually counted) | 2012 List B (all mixes excluded) | 2012 List C (all mixes excluded) |
| Shepherd, German (from pred GSD lists only) | 106 | 106 | |
| Shepherd, German (gen'l pop) | 129 | 94 | 64 |
| Shepherd mixes known & recorded | 28 | ||
| Shepherd, mixes unknown | 5 | ||
| ….. and 4 cats! | |||
| ---------------------------------------- | |||
| Airdale | | 1 | |
| Akita | 3 | 2 | 6 |
| American Eskimo Dog | 2 | ||
| Anatolian Shepherd | 2 | ||
| Australian Kelpie | 2 | 2 | |
| Australian Shepherd Heeler | 2 | 2 | |
| Basenji | 2 | 1 | 1 |
| Bassett Hound | 1 | 0 | 1 |
| Beagle | 4 | 0 | 1 |
| Bearded Collie | 1 | 1 | 1 |
| Beauceron | 1 | ||
| Bernese Mountain | 2 | 2 | |
| Border Collie | 15 | 10 | 9 |
| Borzoi | 2 | ||
| Bouvier des Flanders | 1 | ||
| Boxers | 2 | 2 | 4 |
| Briard | 2 | ||
| Bulldog, English | 2 | 2 | 1 |
| Bull Dog, French | 1 | ||
| Canaan | 1 | ||
| Cane Corso | 1 | 0 | |
| Catahoola | 2 | 2 | |
| Cattle Dog | 11 | 5 | 3 |
| Chihuahua | 4 | 3 | 1 |
| Chinese Crested | 2 | 2 | 1 |
| Chow | 6 | 1 | 1 |
| Collie | 6 | 2 | 3 |
| Corgi | 8 | 6 | 9 |
| Coton du Tulear | 1 | 1 | 1 |
| Dalmation | 4 | 2 | |
| Daschund | 7 | 7 | 6 |
| Doberman | 5 | 4 | 1 |
| Eurasier | 3 | 3 | 1 |
| French Brittany | 1 | ||
| German Shorthair Pointer | 2 | 1 | 1 |
| Golden doodles | 2 | ||
| Great Dane | 2 | 1 | 8 |
| Great Pyreness | 3 | 3 | 2 |
| Greater Swiss Mountain Dogs | 1 | 1 | 4 |
| Greyhound | 6 | 3 | 2 |
| Griffon | 1 | 0 | |
| Havanese | 2 | 1 | 1 |
| Hound | 1 | 1 | |
| Husky | 8 | 2 | |
| Irish Wolf Hound | 1 | ||
| Japenese Chin | 1 | ||
| Komondor | 1 | ||
| Keeshound | 1 | 0 | |
| Kuvasz | 2 | ||
| Labrador | 28 | 7 | 10 |
| Labradoodle | 1 | ||
| Malmamute | 3 | 2 | |
| Maltese | 3 | 2 | |
| Mastiff | 2 | 1 | 3 |
| New Foundland | 3 | 2 | 7 |
| Norwegian Elk | 1 | 1 | |
| Papillon | 2 | 2 | |
| Pekinese | 2 | 1 | |
| Pinsher, Mini | 1 | 1 | |
| Pit Bull | 7 | 2 | 1 |
| Pomeranian | 2 | 2 | |
| Poodle | 9 | 3 | 4 |
| Pug | 3 | 1 | 2 |
| Retriever | 9 | 3 | 8 |
| Retriever, Chesapeke Bay | 1 | 1 | |
| Retriever, Nova Scotia Duck Tolling | 1 | 1 | |
| Rhodesian Ridgeback | 1 | 1 | |
| Rotweiller | 7 | 5 | 3 |
| Saluki | 2 | 1 | |
| Samoyed | 3 | 3 | 1 |
| Schnauzer | 4 | 3 | 1 |
| Setter, English | 2 | 2 | |
| Setter, Irish | 1 | 0 | |
| Sharpei | 1 | 1 | |
| Sheepdog, Belgium | 1 | 1 | |
| Sheepdog, Shetland (shelties) | 8 | 6 | 6 |
| Sheepdog, Tervuren | 1 | ||
| Shepherd, Australian | 4 | 1 | 3 |
| Shepherd, Australian mini | 1 | ||
| Shepherd, Central Asian | 1 | ||
| Shepherd, Shiloh | 16 | 16 | 20 |
| Shepherd, White | 4 | 3 | |
| Shiba Inu | 3 | 1 | |
| Shitzu | 2 | 0 | |
| Spaniel, Cavalier King Charles | 5 | 5 | 5 |
| Spaniel, Cocker | 6 | 4 | 1 |
| Spaniel, English Springer | 3 | 3 | 1 |
| Terrier, Australian | 1 | 1 | 1 |
| Terrier, Border | 2 | 1 | |
| Terrier, Boston | 6 | 5 | |
| Terrier, Cairn | 6 | 6 | 13 |
| Terrier, Jack Russell | 8 | 4 | |
| Terrier, Manchester | 1 | 1 | |
| Terrier, Rat | 2 | 2 | |
| Terrier, Staffordshire (Amer & Bull) | 2 | 2 | |
| Terrier, West Highland | 5 | 5 | 11 |
| Terrier, Wire Fox | 1 | 1 | |
| Terrier, Yorkshire | 3 | 3 | 2 |
| Vizsla | 1 | 1 | 3 |
| Water Dog, Portugese | 2 | 2 | 4 |
| Water Dog, Spanish | 11 | 11 | 4 |
| Weimaraner | 2 | 1 | 2 |
| Whippet | 5 | 3 | 3 |
| Wolf Hybrid | 1 | 1 | 1 |
| non-GSD | 332 | 213 | 214 |
| just GSD's | 235 | 200 | 64 |
| all dogs | 600 | 413 | 278 |
| and cats have EPI too! | 4 | 4 | |
| % of EPI dogs that are not GSD | 55% | 51% | 77% |
| List of ALL mixes excluded from B List: | |||
| GSD, Ridgeback,Lab | 1 | ||
| GSD, Pit, Chow | 1 | ||
| GSD, Beagle | 1 | ||
| GSD, Collie | 2 | ||
| GSD, Chow, Aust Shep, Shiba Inu | 1 | ||
| GSD, Lab | 7 | ||
| GSD, Lab, Rottie | 1 | ||
| GSD, Retriever, Husky | 1 | ||
| GSD, Whippett | 1 | ||
| GSD, Husky | 3 | ||
| GSD, Husky, Whippett, Greyhound | 1 | ||
| GSD, Terrier | 1 | ||
| GSD, Lab, Border Terrier | 1 | ||
| GSD, Cattle Dog | 2 | ||
| GSD, Wolf Hybrid | 1 | ||
| GSD, Border Collie, Husky | 1 | ||
| GSD, Border Collie | 1 | ||
| GSD, Malmamute | 1 | ||
| Great Dane, Weimaramer | 1 | ||
| Lab, Sharpei, Pit | 1 | ||
| Lab, Border Collie, Saluki | 1 | ||
| Lab, Dalmation | 1 | ||
| Lab, Doberman | 1 | ||
| Lab, Greyhound | 2 | ||
| Lab, Pit | 1 | ||
| Lab, Mastiff | 1 | ||
| Lab, Keeshound | 1 | ||
| Pug, Jack Russell | 1 | ||
| Pug, Shitzu | 1 | ||
| Norwegian Elkhound, Akita, Husky | 1 | ||
| Basenji, Cattle Dog | 1 | ||
| Chow, Sheltie | 1 | ||
| Chow, Newfie, Flatcoat Retriever | 1 | ||
| Cocker Spaniel, Retriever | 1 | ||
| Cocker Spaniel, Poodle | 1 | ||
| Maltese, Poodle | 1 | ||
| Golden Doodle | 1 | ||
| Collie, Whippett | 1 | ||
| Collie, Beagle | 1 | ||
| Collie, Cattle Dog | 1 | ||
| Griffon, Boston Terrier | 1 | ||
| Corgi, Chihuahua | 1 | ||
| Corgi, Border Collie | 1 | ||
| Jack Russell, Beagle | 1 | ||
| Jack Russell, Shiba Inu | 1 | ||
| Schnuaser, Bassett, Beagle | 1 | ||
| Sheltie, Australian Shepherd | 1 | ||
| Poodle, Shitzu | 1 | ||
| Labradoodle | 1 | ||
| Pitt, Corso | 1 | ||
| Retriever, Irish Setter | 1 | ||
| total mixes | 62 | ||
| GSD mixes | 28 | ||
METHODOLOGY
Although not a "controlled" study, this data is very telling.......
List A:
Is ALL the dogs.... with the mixed breeds included.... the way i calculated List A with the mixed breed is, for example if a mixed breed came in that was part GSD, Dobie, Husky.... then i gave EACH breed (GSD, Dobie, Husky) 1 credit to cover all the breeds since this is one way of looking at it because we do not know for sure which specific breed might be a possible carrier. Data collected was in 72 hours by EPI owners write-in emails.
List B:
Is the same list as List A but with ALL the mixed breeds excluded. Only known single breeds were included in this list. A list of all the mixes and included it at the bottom of the data sheet so you can see the actual numbers of the GSD mixes (28) and the greater list of non-GSD mixes (34) that also have EPI. Data collected in 72 hours by EPI owners write-in emails.
List C:
This list is not from the email blast this weekend but rather from Enzyme Diane's list of who purchases enzymes from her that she had the dog's breed listed for in her database. This data she already had. We thought it might be telling to see two different sets of data.
| BREEDS Airedale | Coton du Tulear | Pembroke Welsh Corgi |
MIXED BREEDS Anatolian Shepherd/Malamute mix | Golden Retriever/Brittany Spaniel mix |
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