We are very pleased to announce that Dr. Leigh Anne Clark at Clemson University has submitted a proposal to The Morris Animal Foundation http://www.morrisanimalfoundation.org/ with regards to a study EPI in Breeds other than the German Shepherd Dog.
Thank you Dr. Clark http://www.clemsoncaninegenetics.com/ for continuing to pursue the genetics of EPI.
There has been a dramatic shift in breeds afflicted with EPI. It previously was predominantly a GSD or a Rough Coated Collie disease. Then it became approximately a 70% GSD disease. Currently 55% of EPI breeds are something other than the GSD! The tide is changing and we desperately need to understand..... why EPI is happening.....what is triggering it....can we do anything to prevent it????
The following data results were used in a preliminary submission by Dr. Leigh Anne Clark at Clemson University for a proposal on
"EPI Research in Breeds Other than the German Shepherd Dog"
as of the November 2012 AKC declined funding for this EPI research
Thank you to EVERYONE who participated. Your data helped support both of these submission!
In an effort to hopefully help the EPI Geneticists, Drs. Leigh Anne Clark and Kate Tsai at Clemson University, secure additional funding needed to further their EPI genetic Research....epi4dogs requested email submissions from EPI owners identifying the breed of their dog. The response was beyond over-whelming!!!! THANK YOU!!
In order to gather truly random results, I purposely did not give the specifics of what the funding was for and simply asked for all breeds, but the stats we needed were to show how many non-GSD breeds are developing EPI.
The results were eye-opening. Just from our random snapshot data, the pool of non-GSD breeds developing EPI are now becoming greater than just the GSD pool.
Based on data collected from two sources only (epi4dogs & EnzymeDiane) we now know of only 11% of AKC - recognized Pure-bred Canine Breeds that have not yet been diagnosed with EPI
The results are as follows (revised 3/23/12) :
In a random snapshot of time (72 hours) we received 509 responses from TLI confirmed EPI owners:(1) From the general population, only 200 were GSDs = 39% GSDs, 61% were all other breeds
|BREEDS||2012 List A |
|2012 List B |
|2012 List C |
|Shepherd, German (from pred GSD lists only)||106||106|| |
|Shepherd, German (gen'l pop)||129||94||64|
|Shepherd mixes known & recorded||28|
|Shepherd, mixes unknown||5|
|….. and 4 cats!|
|American Eskimo Dog||2|
|Australian Shepherd Heeler||2||2|
|Bouvier des Flanders||1|
|Bull Dog, French||1|
|Coton du Tulear||1||1||1|
|German Shorthair Pointer||2||1||1|
|Greater Swiss Mountain Dogs||1||1||4|
|Irish Wolf Hound||1|
|Retriever, Chesapeke Bay||1||1|
|Retriever, Nova Scotia Duck Tolling||1||1|
|Sheepdog, Shetland (shelties)||8||6||6|
|Shepherd, Australian mini||1|
|Shepherd, Central Asian||1|
|Spaniel, Cavalier King Charles||5||5||5|
|Spaniel, English Springer||3||3||1|
|Terrier, Jack Russell||8||4|
|Terrier, Staffordshire (Amer & Bull)||2||2|
|Terrier, West Highland||5||5||11|
|Terrier, Wire Fox||1||1|
|Water Dog, Portugese||2||2||4|
|Water Dog, Spanish||11||11||4|
|and cats have EPI too!||4||4|
|% of EPI dogs that are not GSD||55%||51%||77%|
|List of ALL mixes excluded from B List:|
|GSD, Pit, Chow||1|
|GSD, Chow, Aust Shep, Shiba Inu||1|
|GSD, Lab, Rottie||1|
|GSD, Retriever, Husky||1|
|GSD, Husky, Whippett, Greyhound||1|
|GSD, Lab, Border Terrier||1|
|GSD, Cattle Dog||2|
|GSD, Wolf Hybrid||1|
|GSD, Border Collie, Husky||1|
|GSD, Border Collie||1|
|Great Dane, Weimaramer||1|
|Lab, Sharpei, Pit||1|
|Lab, Border Collie, Saluki||1|
|Pug, Jack Russell||1|
|Norwegian Elkhound, Akita, Husky||1|
|Basenji, Cattle Dog||1|
|Chow, Newfie, Flatcoat Retriever||1|
|Cocker Spaniel, Retriever||1|
|Cocker Spaniel, Poodle||1|
|Collie, Cattle Dog||1|
|Griffon, Boston Terrier||1|
|Corgi, Border Collie||1|
|Jack Russell, Beagle||1|
|Jack Russell, Shiba Inu||1|
|Schnuaser, Bassett, Beagle||1|
|Sheltie, Australian Shepherd||1|
|Retriever, Irish Setter||1|
Although not a "controlled" study, this data is very telling.......
Is ALL the dogs.... with the mixed breeds included.... the way i calculated List A with the mixed breed is, for example if a mixed breed came in that was part GSD, Dobie, Husky.... then i gave EACH breed (GSD, Dobie, Husky) 1 credit to cover all the breeds since this is one way of looking at it because we do not know for sure which specific breed might be a possible carrier. Data collected was in 72 hours by EPI owners write-in emails.
Is the same list as List A but with ALL the mixed breeds excluded. Only known single breeds were included in this list. A list of all the mixes and included it at the bottom of the data sheet so you can see the actual numbers of the GSD mixes (28) and the greater list of non-GSD mixes (34) that also have EPI. Data collected in 72 hours by EPI owners write-in emails.
This list is not from the email blast this weekend but rather from Enzyme Diane's list of who purchases enzymes from her that she had the dog's breed listed for in her database. This data she already had. We thought it might be telling to see two different sets of data.
Coton du Tulear
Pembroke Welsh Corgi
Anatolian Shepherd/Malamute mix
Golden Retriever/Standard poodle mix
Buddy Lee is a Chihuahua who suffered for a couple of years before the vets realized it COULD be EPI. It wasn't until his drastic weight loss that anyone really took notice. Up until then, it was passed off as stomach upset, colitis or IBS. I knew it was none of the above. I also knew my dog was in a lot of pain, a lot of the time, and Albon or Pepto Bismol did little for him. I also knew he had bowel movements that were downright ugly and I carried many of them to the various vets we saw. I now believe it was a form of pancreatitis, which our bigger dog suffered from but no one suggested it for my Buddy Lee. After he dropped 1.5# (a LOT for a 6# dog) I got information through a Chihuahua meet up site that he might have EPI. I asked my vet to run the test. My vet was surprised when it came back as the diagnosis, as it's generally considered a "Big Dog" problem. My story is that, today, after 6 months of enzyme therapy, I have a happy, healthy, Chihuahua. Last November (2007) I cried every day as I thought each day he was one step closer to passing.
Another Chi owner friend of mine is running up against the same kind of anti EPI prejudice for her dog, who has the exact same symptoms, posture, etc, as my Buddy Lee. Her vet WON'T run the tests. I sent her some Viocase tablets I keep on hand and her dog is making an amazing turnaround. For the first time in over a year, she has become vocal. Wouldn't that make you cry? She's also gained a few ounces. She dropped from 4.9# to 1.9# but is on the way back. The friend's vet has agreed that "IF" she continues to gain weight, he will prescribe the Viocase for her. Unfortunately for her, she lives so far out in the sticks, her veterinary choices are few. Fortunately for her, she lives in Texas, home of TAMU. It's only a matter of ego as her vet could call them anytime for advice.
Thank you for taking the time to read my story of Buddy Lee, let's all work to get the word out....EPI can afflict any breed! Article and pictures are courtesy of Buddy Lee's mom, Kate from KS.