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Adjust enzyme amount?

Posted: 31 Jan 2021, 10:39
by Curtis
Good morning, this is my first post but have been lurking here for a month or so. Thank you to this site and forum for all the info I have gotten from it to understand EPI.

My english bulldog is 11 months old and was diagnosed with epi a month ago. We went from chronic diarrhea for 2 months to being fairly regular since being on the enzymes ( from Enzyme Diane again thanks to this site ).

Her poop for a month has been consistent 4s or 5s according to the poop chart and some days 2 poops and some days as many as 5. We are happy with that because we had months of diarrhea. My question is SHOULD I be happy with that or should I be adjusting the enzymes a bit? Today she gets exactly 1 cup of kibble and 1 tsp of enzyme per meal (properly incubated ) and no other food /treats at all. Do I adjust up, down, or leave it? If I adjust do I do it for a couple of days and see what happens or will I know right away?

Thanks in advance everyone, i am so glad to have found this group.

Curtis

Re: Adjust enzyme amount?

Posted: 31 Jan 2021, 10:51
by jilbert57
Hi Curtis and welcome to you two. Will you post the results of the Tli for us. Also was the B12 also tested? Sounds like you are managing the Epi pretty well but there may be some tweaks.

I believe I would leave the enzymes where you have them. Are they 6x in strength?

What food are you feeding? We usually recommend grain free, 4% fiber or less and if it contains peas or legumes please may it be 4th or further down on ingredient list.

Most dogs have low B12 when diagnosed. It needs to be in the upper mid range or higher. This can be oral supplement or B12 shots weekly.

Have you heard tummy rumblings, gas, burps?
Most pups have SID/SIBO when diagnosed with EPI and a 45 day course of Tylan is recommended. You can also use Slippery elm in place of Tylan first to see if it helps.

Jill

Re: Adjust enzyme amount?

Posted: 31 Jan 2021, 11:13
by Curtis
Sorry I do not know the TLi score. Her b12 was tested and was fine. I am using the 6x. She is on a limited ingredient, grain free kibble with no peas legumes etc and 4% fibre content (again thanks to the info here!) Prior to her being diagnosed her guts were very rumbly and gassy but not at all since being on the enzymes. She seems perfect in every way now with the exception that I am not sure her poop is quite where it should be according to the chart. Thanks again for helping!

Re: Adjust enzyme amount?

Posted: 31 Jan 2021, 11:34
by Madelon
Hi Curtis - welcome to our Forum. If you are not supplementing B12 and it's been a month since diagnosis I would recommend getting the B12 tested again. EPI dogs need their B12 on the high side of normal 600+ - so while your vet said the B12 was good it might not be good enough for an EPI dog. Supplementing B12 is for life with these dogs and low B12 can affect weight, mood, appetite and yes the poop.

So if it were me, before adjusting the enzymes I would try to find out from the vet what the B12 was at the time of testing for EPI and then either go ahead and start supplementing the B12 or get it tested again and then start supplementing.

Re: Adjust enzyme amount?

Posted: 31 Jan 2021, 17:03
by Tuckaboo Pam
And, Curtis, if you do decide to just start supplementing, try to get Wonderlabs B12 w/intrinsic factor. Amazon has it, it's all Tucker has ever taken, and he's doing well. ---Pam

Re: Adjust enzyme amount?

Posted: 31 Jan 2021, 17:29
by Olesia711
HI Curtis and welcome to our EPI family.

B12
As mentioned in the other posts.... call your vet and find out exactly what the B12 test results were.... and post here. Too many times we have heard the vets say the B12 was fine and because it was in the normal range or low normal... neither are good enough for an EPI dog as they all have SID (small intestinal dysbiosis) to one degree or another....and SID munches away at any B12 reserves..... so with EPI dogs, the B12 can plummet dramatically. Even once you achieve upper mid range B12.... you need to supplement it with a maintenance level of B12 (this is if it wasn't upper mid-range to begin with). SO... All this just to say, no matter what.... check on the B12.. It is very important to the overall recovery of an EPI dog.

Because the poos are better but not exactly optimal.... it usually means that things are not optimal for your dog...
1. First thing we look at is food..... and even though it may fit all the suggested parameters for an EPI dog. SOOOOOOOOOOO..... after checking into the B12 results...(you just need to make sure this is being addressed properly) and before changing the food ... yes..... i would slightly increase the enzymes by a pinch. I am assuming you are giving 1 level tsp of 6x to 1 cup of food... correct? if yes...then add 1/8 tsp more enzymes to the food.

or.

2. you can try incubating the food 1o minutes longer with the current amount of enzymes you are giving.... see if that improves things.

3. Another thing you can try (just don't do all these things at once.....pick one thing at a time and try it for a few days before trying the next thing) would be to start adding a prebiotic to the meal or a prebiotic and probiotic. Like you said there was a lot of gas, etc in the beginning... that is SID. SID never really goes away completely, but rather we do whatever we can to get it and keep it in good control. With EPI dogs, they have discovered that all EPI dogs have messed up gut flora. Not enough of a bacterial population in the gut AND the variety of gut bacteria is lacking..... so we suggest (to help keep the gut as healthy as we can) if there seems to be any issues, add a prebiotic (many of us try slippery elm powder)... or add a probiotic with prebiotics in it. We ALWAYS suggest starting off with less than half the dose and working your way up to giving a full dose over the course of a week or two.

4. If none of the above works.... then i would next suggest a course of Tylan antibiotic .... or..... a change in the food. it might be that the protein source is not the most agreeable OR sometimes it is simply that there is too much of one particular ingredient or too many carbs in the food.... you just never know with these dogs.

Re: Adjust enzyme amount?

Posted: 31 Jan 2021, 17:47
by Curtis
Wow, love the responses folks, absolutely astonishing!

I will contact my vet tomorrow to get my tli and b12 scores and post them here. Thanks again, it is truly appreciated.

Re: Adjust enzyme amount?

Posted: 31 Jan 2021, 23:05
by Olesia711
you are welcome and PLESE keep us posted!

Re: Adjust enzyme amount?

Posted: 01 Feb 2021, 15:46
by Curtis
Here were our test results:

TLI 2.6
Cobalamin 325
Folate >270

Re: Adjust enzyme amount?

Posted: 01 Feb 2021, 17:33
by jilbert57
Hi Curtis,
Thanks for posting the results. Yes I would order Wonderlabs B12 with Intrinsic factor and start with 1 or 2 caps a day. Here is a link:

https://www.wonderlabs.com/itemleft.php?itemnum=K9688
If you order from Wonderlabs you get 15%off if you enter Epi4dogs15 in the coupon.
Not sure what the price is on Amazon.

I suspect the folate is >27, not >270.

Jill