How do I give Heartguard??

Epi4Dogs Foundation Inc.’s mission is the advancement of science and education relating to EPI (Exocrine Pancreatic Insufficiency), yielding useful insights and positive outcomes in better managing EPI in dogs and cats. Our goals are to support and/or collaborate with veterinary EPI research and researchers, and to promote EPI awareness by educating the general public, pet owners, pet organizations, rescue and shelter organizations, veterinary schools and veterinarians.
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How do I give Heartguard??

Post by Landonmom » 31 Aug 2018, 09:46

We have been in enzymes for two weeks now. It’s going ok, I guess. ( blood work will be done next week to check levels) . But Landon gets chewable Heartguard , and tomorrow is his day again for it. How should I administer it????? My guess is to cut it up and put it in his regular meal and incubate it .... but, I’m asking the experts ! Thank you for your help !

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Re: How do I give Heartguard??

Post by jilbert57 » 31 Aug 2018, 09:53

Hi. If it was me I would give his Heartguard right after he is done eating. That way the enzymes are still present.
My name is Jill and I live on the Hood Canal in Washington State. I have two dogs: Kiya is an aussie/blue heeler and is 13, TJ is a 4 year old Jack Russell. They keep me on my toes.
Mickey and his pancreatitis brought me to site in 2012 to help manage it.

Mickey, Jack Russell. Chronic Pancreatitis. Dianes enzymes, 1/8t 3x/day with meals.
6/1999 - 8/2014

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My name: Jean

Re: How do I give Heartguard??

Post by Jean » 31 Aug 2018, 10:24

i have always thought that you dont need to enzyme medication, but I have never had to use heartworm meds,

so to be safe give it with food, and enzymes


Does Heartgard need to be given with food?
Give this medication with or without food. The medication is meant to be chewed before swallowing. It may be necessary to break the chewable into smaller pieces and hand feed as treats. Ensure that your pet consumes the entire dose.,


this is from their website

My name is Jean we live in Liverpool in Uk

My Kara born 21 July 2009 diagnosed with EPI by cTLI test August 2010 TLI = <1...folate 14 Cobalamin 408, shot down to 94, b12 injections every other day

Lowest weight 39 pounds

We use Panzym enzymes, Tylan and Chemeyes b12 capsules

Sadly, on 10th May 2019, we lost her to DM


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Location: Nashville, TN
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Re: How do I give Heartguard??

Post by Madelon » 31 Aug 2018, 12:30

I have always just given it at mealtime.
MADELON and Doc. DX EPI and SIBO: 5/22/2015
Test Results: (1st) 7/2014 = TLI 16.5, B12 894, Folate > 24; (2nd) 5/2015 = TLI < .4, B12 406; Folate >24; (3rd) 10/2015 TLI < .4; B12 >1000; Folate 14.4. Prior to DX: May 2014 (2mos) - DX coccidia/bladder infection; July 2014 (3mos) 1st EPI test = TLI 16.5, B12 894, Folate >24 - Dx SIBO not EPI; Feb 2015 thru May 2015 - weight loss only; May 2015 vomitted several times, diarrhea and eating poop. Regimen: 4 cups Sport Dog Food Elite Herding - Diane 6x 1tsp per cup; 1 WonderLab PetFactor B12 2x day; 1/2tsp Slippery Elm 2xday; Multivitamin; 1 Zyrtec 10mg 2x day; Salmon Oil

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Re: How do I give Heartguard??

Post by Barb » 31 Aug 2018, 16:18

I have always given Kolby his heartworm med just by breaking it into a few pieces and putting it on the enzymed food right before he eats. I have never incubated it and it's been fine this way.


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Re: How do I give Heartguard??

Post by Olesia711 » 01 Sep 2018, 15:40

No need to incubate heartworm med... just give as mentioned above .. either right before or after a meal :)

Also.... no need to stop giving heartworm med or tick and flea med just because a dog has EPI.... The only thing i personally suggest is to not give heartworm and tick and flea meds on the same day.... i like to suggest giving a week apart :)... simply because that is aa lot of chemicals all at once to give a dog with a compromised system......
Olesia, was owned by Izzy, a 35lb Spanish Water Dog (SWD), Diagnosed at 1.5 years old - TLI results 1.. Izzy passed away on February 13, 2020 at 15 years old. She lived with EPI for 13+1/2 years. It was because of Izzy that Epi4Dogs was started... she was the inspiration. May her legacy of helping others with EPI continue for as long as needed.........

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