However... due to the complexity of the study, myself and Dr. Barko worked on summary explanations of the study to better help folks understand how the research was done and how to interpret the results. Below is my summary, but please go to our EPI RESEARCH page to see both Dr. Barko's (and mine is also included) summary explanations and PDF to the actual study results
https://epi4dogs.com/epi-research/
Olesia Kennedy
Epi4Dogs Foundation, Inc.
www.epi4dogs.com
[email protected]
7 September 2023
New Research Report Has Identified New Metabolic Markers for
Exocrine Pancreatic Insufficiency in Dogs
Epi4Dogs Foundation Inc.’s purpose is to advance science and education of EPI
Exocrine Pancreatic Insufficiency (EPI) in dogs by raising funds for EPI research
that will yield useful insights or positive outcomes to improve the diagnosis and
treatment of the disorder. Epi4Dogs Foundation Inc. has assisted and collaborated with
various veterinary investigators to advance studies of the genetics, gastrointestinal, and
nutritional aspects of EPI.
We are thrilled to announce the results of a recent investigation of metabolism in
dogs with EPI. This research was led by a team of investigators at the University of
Illinois, including Drs. Patrick Barko and David Williams, both board-certified specialists
in small animal internal medicine. This research utilized a cutting-edge method to
measure hundreds of biochemicals involved in metabolic reactions in the blood
of dogs with EPI and compare them to healthy dogs. This approach is called
“untargeted metabolomics” and has the potential to reveal new facets of complex
disorders like EPI. The results of this study have generated novel insights into the
impacts of EPI on metabolism in affected dogs, and has revealed new markers that may
aid in the assessment of its impact on gastrointestinal bacteria and resulting intestinal
dysbiosis.
The study was conducted in collaboration with Epi4Dogs Foundation Inc. and several of
our community members participated in this study by donating samples from their own
dogs. This investigation could not have been possible without the assistance and
participation of the Epi4dogs community. In particular, a generous donation from
Paula and John Gatens was vital to its success.
Untargeted metabolomics investigations are complex, and I have attached to this
announcement a summary of the study provided from the investigators which is
intended to communicate their findings to an audience of non-scientists.
Sincerely,
Olesia Kennedy
Founder, Epi4Dogs Foundation Inc
