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Re: Tylosin dose

Posted: 04 Dec 2022, 09:58
by jilbert57
Have you or your vet looked into the Tagamet/Benadryl protocol for the mast cell tumor?

https://dogcanceranswers.com/tagamet-an ... deep-dive/

Jill

Re: Tylosin dose

Posted: 04 Dec 2022, 11:05
by Tuckaboo Pam
Coconut oil, along with having antibiotic & antimicrobial properties, is also an antifungal. Dogs love it, too. If you got it to a liquid form, and he lapped up a teaspoon a few times a day, maybe enough residue would stay behind to be effective.

I also wonder if you could paint his gums with the stuff used on newborns who have thrush?

Re: Tylosin dose

Posted: 04 Dec 2022, 11:51
by Jean
Try ice cubes in his mouth, they will often chew on them

the one thing with sore mouths is a flat glass pie plate of some sort or a glass dinner plate for food

i am wondering if he might have an intolerance to porcine

the chart for Tylan is here

https://epi4dogs.com/antibiotics/

as far as food is concerned the recommendation is 50% over and above what the food bag instructions say for the weight the dog SHOULD be over several meals a day, if you can fit it in, all enzymed the Tylan should be twice daily withat least 8 hours between doses longer if you can

any biotics should be given as far away from the Tylan dose as possible, so in between ish

I do commiserate, Kara was just like this at the start

Re: Tylosin dose

Posted: 04 Dec 2022, 12:37
by Chance
jilbert57 wrote: 04 Dec 2022, 09:58 Have you or your vet looked into the Tagamet/Benadryl protocol for the mast cell tumor?

https://dogcanceranswers.com/tagamet-an ... deep-dive/

Jill
He is on Benadryl for his tumor. Tagamet no longer exists here. But as it was a prescription item before pulling it, chances are it would be stopped in Customs if I did try ordering from US.

He was on Pepcid (also H2 blocker) until the most recent acid reflux issue, then temporarily switched to a PPI.

Re: Tylosin dose

Posted: 04 Dec 2022, 12:53
by jilbert57
Interesting. We can buy it on Amazon. I used the protocol way back in 1996 OTC.

Jill

Re: Tylosin dose

Posted: 04 Dec 2022, 13:03
by Chance
jilbert57 wrote: 04 Dec 2022, 12:53 Interesting. We can buy it on Amazon. I used the protocol way back in 1996 OTC.

Jill
Canada is backwards when it comes to enzymes and antacids! You can buy enzymes in your corner store, or off Amazon.

We do have Nexium over the counter; but it's kept behind the counter. So not something I could order online; but something I can try if for whatever reason isn't able to get back on Pepcid. All other antacids are prescription only. (I do prefer Pepcid, as it's an H2 histamine blocker, and that is what is secreted by the tumor).

Re: Tylosin dose

Posted: 03 Jan 2023, 13:07
by Chance
Hi again!

Ok, things have been high and low here. Changing vets, yet again. My original vet, which I was leaving anyway has closed down.

My concern was/is that Chance stopped eating. He's a Lab. Food is extremely important to a Lab! It's very strange for him. Vet I did go to says it's likely a tooth root abscess. Nothing we can do, he can't have an anesthetic. Pump him full of pain meds.

I went to another vet. They did x rays and looked at his teeth. No signs of abscess and no signs of pain in his mouth. Problem is not teeth. (They fed him while there, which they didn't tell me, so had interesting looking poops the next day! I even had his pills with me in case they wanted to feed him 🙄)

Ok, so next step was to run full blood work again, including a GI panel. (I agreed to that only because I wanted to ensure my B12 frequency was ok). I don't have numbers as we spoke on the phone

TLI Very low (big surprise there)
Folate quite LOW
Cobalamin upper range normal

Folate is my biggest question. He's on Baytril (now low dose) to keep SIBO at bay. Poop is mostly good. Vet (no experience with EPI) wants me to start a Folate supplement. (He's very sensitive to Tylosin, so I can't give that again)

B12 was read exactly 10 days post injection. I have been injecting every other week. I am told to keep the bi weekly injections the same.? Or maybe I can go to 3 week cycle?

Cortisol levels low. Having had a dog with Addison's disease for 16 years, this to me is a concern. Vet is less concerned. Addison's wouldn't pop up all of a sudden now. (I agree with that completely. But what if there's something else somewhere that's causing the adrenals not to work as expected)? It would take a few weeks to get results of ACTH)

Anyway, biggest question is Folate levels. My understanding was high Folate was typically associated with EPI because of SIBO. ?? Do I start Folate supplement as he suggests?

Re: Tylosin dose

Posted: 04 Jan 2023, 10:11
by jilbert57
I would look possibly at the Baytril for loss of appetite. Even if Chance has been on it awhile loss of appetite is a symptom of side effects.
Low folate:
https://vcahospitals.com/know-your-pet/ ... production.

Jill

Re: Tylosin dose

Posted: 04 Jan 2023, 15:21
by Chance
Antibiotics was my first thought. We took him off antibiotics for a few days (back when it first started). It didn't help. It only got worse. Tried a different antibiotic after those few days off (doxy). But that seemed to cause vomiting and diarrhea.