Micrazym 25,000

Epi4Dogs Foundation Inc.’s mission is the advancement of science and education relating to EPI (Exocrine Pancreatic Insufficiency), yielding useful insights and positive outcomes in better managing EPI in dogs and cats. Our goals are to support and/or collaborate with veterinary EPI research and researchers, and to promote EPI awareness by educating the general public, pet owners, pet organizations, rescue and shelter organizations, veterinary schools and veterinarians.
Chance
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My name: Andrea

Re: Micrazym 25,000

Post by Chance » 21 Oct 2024, 12:36

BUT...you gave half tsp of enzymes Diane per meal? Roughly 50,000 lipase units per meal.

If the enteric coated capsule dose is half of the enzyme Diane dose (because of the enteric coating), then Eddie might actually need up to a full capsule (25,000) per meal??? It seems like a lot though, for a little guy.
Chance was my 4 legged soul mate. My mobility assist service dog. Pure yellow Lab, 75 lbs. After struggling with weight all his life, finally dx with EPI. cTLI < 1, folate and B12 very low. Fed Raw. Maintained with Creon, Garden of Life probiotic and intermittent calcium bentonite clay. (Tylosin was a big nightmare for him)!

Rylee is Chance's successor; also pure Yellow/Fox red Lab. Started with symptoms at 8 weeks. At 6 months of age, also prescribed Creon due to suspected EPI (due to passing large amounts of undigested food). Currently suspected of blockages in pancreatic ducts. She is maintained VERY nicely on Creon and probiotics. Also raw fed.

Eddiespaghetti
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My name: Jeremy

Re: Micrazym 25,000

Post by Eddiespaghetti » 21 Oct 2024, 14:20

You all are correct. What happened in my brain is I also imported some Creon 10,000. Assuming I would be giving a capsule per meal. At 50 pack it would last 25 days. I got my medication mixed up. At 50 days it makes it a lot more cost effective than.
On to the lipase math. 8X is 104,000 per teaspoon. He gets a little more than half of teaspoon, let's say 60000. When we were doing the coated capsules it was about 1/8-1/4th of a teaspoon. 13-25000. It's really hard to measure this tiny amounts into grams and be accurate. He will need somewhere pretty half to one capsule per meal. It has been almost 48 hours and everything seems to be going well. I think his transit time has been about 16 hours, so we should be into the micrazym at this point.

Tuckaboo Pam
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Re: Micrazym 25,000

Post by Tuckaboo Pam » 21 Oct 2024, 17:09

Sorry, Jeremy. The link took me to a box of 50.

My brain said---1/2 X 2 meals=1 per day, and 50 capsules at $42.00ish means the box lasts 50 days.

I've never used 8X, so maybe that's where I'm confused. It's OK. There are better things to focus on than my math skills.
Tucker was a shepherd mix--- TLI 1.3, Folate 9.7, Cobalamin 666, Lipase 38. Diane's Enzymes 4 t/day, B12 1 capsule/day, and Tylan 1/16 teaspoon/day. Taste of the Wild High Prairie, 4 c/day. 60 to 85 pounds! Tucker succumbed to hemangiosarcoma Nov. 2023. I will always, always miss my sweet big boy.

Now there's Nina. 5 year old GSD. TLI 1.0 B12 323. We are still tweaking her routine, and getting lots of help from the forum. She is klutzy and goofy, and we love her dearly, too.

Chance
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Re: Micrazym 25,000

Post by Chance » 21 Oct 2024, 17:31

Ah okay, so your working with Creon and Micrazym on the brain. That makes more sense.

In a way it's good to have both. Compare to see if Micrazym is as good as Creon

That makes sense with anywhere between half to full capsule of Micrazym. If he does well on just one capsule per day, it would be very good, cost wise. It would be less cost effective for Rylee. Nothing cost effective for her :(
Chance was my 4 legged soul mate. My mobility assist service dog. Pure yellow Lab, 75 lbs. After struggling with weight all his life, finally dx with EPI. cTLI < 1, folate and B12 very low. Fed Raw. Maintained with Creon, Garden of Life probiotic and intermittent calcium bentonite clay. (Tylosin was a big nightmare for him)!

Rylee is Chance's successor; also pure Yellow/Fox red Lab. Started with symptoms at 8 weeks. At 6 months of age, also prescribed Creon due to suspected EPI (due to passing large amounts of undigested food). Currently suspected of blockages in pancreatic ducts. She is maintained VERY nicely on Creon and probiotics. Also raw fed.

Eddiespaghetti
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Pet name: Eddie
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Re: Micrazym 25,000

Post by Eddiespaghetti » 21 Oct 2024, 18:29

Even at 1 capsule a meal. The cost isn't that much more. It might be worth it, if it works. The nice thing is it comes from Amazon so usually a day or two shipping time. Enzyme Diane is usually pretty quick but not that fast. With them being coated pellets, hot and cold shouldn't affect it. Sometimes we feed Eddie the fresh pet, farmer's dog, refrigerator food. Of course hopefully not having to worry about them being moistened properly for the mouth sores is a huge plus.
One thing I am going to try once we get everything established is grain. I am curious to see if the coated pellets are affected by grain as much.

Eddiespaghetti
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Re: Micrazym 25,000

Post by Eddiespaghetti » 02 Nov 2024, 15:24

Sorry for the delayed updates. Life has been incredibly tough. We had to send Emma down the rainbow road. He cancer progressed too fast. It ended up completely collapsing one of her lungs. After losing Emma and Maggie in the same month it has been tough to find any energy.

Eddie is doing well though. After a lot of trial and error we have discovered one 25000 micrazym per 3/4th cup is the perfect amount.

We have also found out giving the whole capsule, not so good. Opening it up and sprinkling it on his food works much better.

Tuckaboo Pam
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Re: Micrazym 25,000

Post by Tuckaboo Pam » 02 Nov 2024, 19:03

Jeremy, I am so, so sorry to hear this bad news. I know Maggie's passing was devastating to you, and I can't even imagine how sad you must be, losing Emma too. Warm thoughts to you and Eddie, who must be feeling this, also.

Thank you for the enzyme update. ----Pam & Nina
Tucker was a shepherd mix--- TLI 1.3, Folate 9.7, Cobalamin 666, Lipase 38. Diane's Enzymes 4 t/day, B12 1 capsule/day, and Tylan 1/16 teaspoon/day. Taste of the Wild High Prairie, 4 c/day. 60 to 85 pounds! Tucker succumbed to hemangiosarcoma Nov. 2023. I will always, always miss my sweet big boy.

Now there's Nina. 5 year old GSD. TLI 1.0 B12 323. We are still tweaking her routine, and getting lots of help from the forum. She is klutzy and goofy, and we love her dearly, too.

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Olesia711
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Re: Micrazym 25,000

Post by Olesia711 » 02 Nov 2024, 20:19

JEREMY,

My heart goes out to both you and Jax not only for losing Maggie, but now Emma too... and so close to each other. this is so heart-breaking....... my deepest condolences!
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Olesia, was owned by Izzy, a 35lb Spanish Water Dog (SWD), Diagnosed at 1.5 years old - TLI results 1.. Izzy passed away on February 13, 2020 at 15 years old. She lived with EPI for 13+1/2 years. It was because of Izzy that Epi4Dogs was started... she was the inspiration. May her legacy of helping others with EPI continue for as long as needed.........

Chance
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My name: Andrea

Re: Micrazym 25,000

Post by Chance » 03 Nov 2024, 00:42

Awww no. So very sorry for your Loss! It's truly very difficult to say goodbye. RIP Emma. I know Chance would have come to greet you and be one of the ones to show you around.

It's good you have figured out a Micrazym dose for Eddie!

Just out of curiosity, have you also tried the Creon as yet? Curious to know if that was the same dose as Micrazym (ie: 2.5 caps of the 10,000)?
Chance was my 4 legged soul mate. My mobility assist service dog. Pure yellow Lab, 75 lbs. After struggling with weight all his life, finally dx with EPI. cTLI < 1, folate and B12 very low. Fed Raw. Maintained with Creon, Garden of Life probiotic and intermittent calcium bentonite clay. (Tylosin was a big nightmare for him)!

Rylee is Chance's successor; also pure Yellow/Fox red Lab. Started with symptoms at 8 weeks. At 6 months of age, also prescribed Creon due to suspected EPI (due to passing large amounts of undigested food). Currently suspected of blockages in pancreatic ducts. She is maintained VERY nicely on Creon and probiotics. Also raw fed.

Eddiespaghetti
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Posts: 455
Country: United States
State: California
Pet name: Eddie
My name: Jeremy

Re: Micrazym 25,000

Post by Eddiespaghetti » 03 Nov 2024, 11:53

We did also try the Creon 10000. 2 creon 10000 seems to work the same as 1 micrazym. I am not sure if Eddie only needs 20000 and it's too hard to measure out 4/5th of the micrazym.
I know some people said that Creon is stronger overall. That could also be a reason. I am just glad we got the dosage figured out.

We thank you all for the kind words. We are doing okay, it's just way too quiet in the house now.

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