Re: Allergies to enzymes
Posted: 12 Aug 2019, 17:49
VERY IMPORTANT! There is no accurate test to confirm SID.... there are flaws with all 3 ways of testing for it, and EPI research has already determined that in EPI dogs they ALL have SID.... in lay terms, every single one has a messed up gut flora... not enough bacteria and not enough variety of bacteria... and giving probiotics is not always the answer since currently all probiotics are pretty much a one size fits all... and that doesn't work for a lot of EPI dogs.... they have an over abundance of lactic acid... (read the SID page, specifically look at the research done by Dr. Suchdolski... EPI dogs have off the charts readings
SO.... our goal is (with EPI dogs) to try to manage their SID and the best way to manage it is to find a food that best agrees with each individual EPI dog. Sometimes probiotics help, other times they don't. Prebiotics on the other hand tend to more readily help (SLippery Elm has prebiotic properties )
SO... to assess whether or not an EPI dog has uncontrolled SID and needs serious help (like antibiotics) what you need to do is
1. Assess the health issue concern, like EPI. Is SID prevalent with EPI cases? YES!!!!
2. Are you seeing "repeated" symptoms/signs of SID in your dog, if yes, and if a prebiotic has not been able to fix the problem, then a course of anti's are warranted.... and then once you get it under control, try to figure out what triggered SID to become uncontrolled.
Here is an important "read" on SID:
SID”small intestinal dysbiosis”/SIBO & TREATMENT
Because of the very nature of EPI (pre-diagnosis/treatment) undigested food/ bacteria imbalance/not enough different bacterial strains/ excessive fermentation causes SID/SIBO in all EPI dogs. Goal is to get SID under good management.
In some cases, if EPI is detected very early on, once proper treatment (enzymes) is administered the good gut flora sometimes “may” re-populate the gut flora (bacteria) imbalance rendering antibiotics not necessary. Much success is seen with Slippery Elm powder. Slippery Elm is given with breakfast and dinner. The following are suggested doses for Slippery Elm: 1/8 tsp for dogs under 10lbs, ¼ tsp for dogs 10lbs to 30lbs, ½ tsp for dogs 30lbs to 80lbs, 3/4 tsp for dogs 80lbs to 100lbs, and 1 tsp for dog 100/+lbs. Mix in meal, add 1 to 2 tablespoons of water, mix and serve meal as you normally would. Incubating not necessary. Note: sometimes even less Slippery Elm powder works better. Do not give if the pet has an allergy to the American ElmTree.
However, many will still have to resort to an antibiotic regimen to get SID/SIBO under good management.
The best way to assess SID/SIBO is by (1) symptoms and (2) accompanying medical ailment, in this case EPI, and treat early on for best results. Folate test results such as Culturing, Counting bacterial numbers, and Duodenal juice collection all have majors flaws in their technique rendering them inaccurate indications of SID/SIBO. Recent studies have determined that it is not the number of bacteria but rather “the type of flora and/or how the host and flora interact that are more important than numbers.”
If the dog displays any repeated signs such as yellowish-coloring to the stools, loose stools, gelatinous stool coating, flatulence, lack of appetite, stomach noises, low or low normal B12 then treat for possible secondary SID/SIBO (with Tylosin [preferred] or Metronidazole, or in some cases Amoxycillin. Tylosin appears to work best for the majority of EPI dogs with SID/SIBO.
The current recommended Tylosin dosage has recently been changed to “25mg/kg BID with food for 6 weeks”, but some still prefer to administer twice daily [every 12 hours] with food:
30 lbs – 1/8 tsp 60lb – 1/4 tsp
90 lb – 3/8 tsp 120 lb – 1/2 tsp
A response to the antibiotics should be seen within 7 to 10 days- -if improvement is seen during this time period, indicating that SID/SIBO is present, the antibiotics should be continued for a total 6 weeks, or at the very least a minimum of 4 weeks.
If a positive response is not seen within 7-10 days, change the antibiotic. Most EPI dogs appear to respond best to Tylosin, but if not, switch to Metronidazole (or switch from Metro to Tylan). With exceptionally difficult SI/SIBO cases, historically it has been recommended to continuously repeat or consistently continue antibiotic treatment for life. Although not clinical proven, what has been observed by diligent pet owners is that some are able to completely remove a SID/SIBO-prone dog from antibiotics through a methodical process of slowly reducing the antibiotic dose and interval while slowly introducing an increased inclusion of a safe, stable, and “agreeable” with the individual dog’s intestinal gut flora” pre and/or probiotic
Prebiotics are non-digestible food components (dietary fiber) that are being fermented by intestinal bacteria. Slippery Elm is a prebiotic. This can lead to more normalization of the intestinal microbiota. In a recent study the use of fructooligosaccharides (FOS) in the diet showed a lasting advantageous effect. This syndrome is also a potential target for probiotic therapy but one must be careful when administering probiotics. Too much FOS can cause the opposite effect. Per Dr. Jorg Steiner of Texas A&M University “…unrealistic expectations have been replaced with well-defined requirements for probiotics and controlled studies of their beneficial effects. A probiotic must be efficacious. In order to be efficacious, the bacteria must reach the intestinal lumen. This requires that the bacterial species being used in the formulation are both acid- and bile-acid resistant. Also, the bacterial species of the probiotic preparation should adhere to the intestinal mucosa to prolong the time of interaction.
When possible use a 3rd party laboratory such as http://www.consumerlab.com/ to verify product “claims”
SO.... our goal is (with EPI dogs) to try to manage their SID and the best way to manage it is to find a food that best agrees with each individual EPI dog. Sometimes probiotics help, other times they don't. Prebiotics on the other hand tend to more readily help (SLippery Elm has prebiotic properties )
SO... to assess whether or not an EPI dog has uncontrolled SID and needs serious help (like antibiotics) what you need to do is
1. Assess the health issue concern, like EPI. Is SID prevalent with EPI cases? YES!!!!
2. Are you seeing "repeated" symptoms/signs of SID in your dog, if yes, and if a prebiotic has not been able to fix the problem, then a course of anti's are warranted.... and then once you get it under control, try to figure out what triggered SID to become uncontrolled.
Here is an important "read" on SID:
SID”small intestinal dysbiosis”/SIBO & TREATMENT
Because of the very nature of EPI (pre-diagnosis/treatment) undigested food/ bacteria imbalance/not enough different bacterial strains/ excessive fermentation causes SID/SIBO in all EPI dogs. Goal is to get SID under good management.
In some cases, if EPI is detected very early on, once proper treatment (enzymes) is administered the good gut flora sometimes “may” re-populate the gut flora (bacteria) imbalance rendering antibiotics not necessary. Much success is seen with Slippery Elm powder. Slippery Elm is given with breakfast and dinner. The following are suggested doses for Slippery Elm: 1/8 tsp for dogs under 10lbs, ¼ tsp for dogs 10lbs to 30lbs, ½ tsp for dogs 30lbs to 80lbs, 3/4 tsp for dogs 80lbs to 100lbs, and 1 tsp for dog 100/+lbs. Mix in meal, add 1 to 2 tablespoons of water, mix and serve meal as you normally would. Incubating not necessary. Note: sometimes even less Slippery Elm powder works better. Do not give if the pet has an allergy to the American ElmTree.
However, many will still have to resort to an antibiotic regimen to get SID/SIBO under good management.
The best way to assess SID/SIBO is by (1) symptoms and (2) accompanying medical ailment, in this case EPI, and treat early on for best results. Folate test results such as Culturing, Counting bacterial numbers, and Duodenal juice collection all have majors flaws in their technique rendering them inaccurate indications of SID/SIBO. Recent studies have determined that it is not the number of bacteria but rather “the type of flora and/or how the host and flora interact that are more important than numbers.”
If the dog displays any repeated signs such as yellowish-coloring to the stools, loose stools, gelatinous stool coating, flatulence, lack of appetite, stomach noises, low or low normal B12 then treat for possible secondary SID/SIBO (with Tylosin [preferred] or Metronidazole, or in some cases Amoxycillin. Tylosin appears to work best for the majority of EPI dogs with SID/SIBO.
The current recommended Tylosin dosage has recently been changed to “25mg/kg BID with food for 6 weeks”, but some still prefer to administer twice daily [every 12 hours] with food:
30 lbs – 1/8 tsp 60lb – 1/4 tsp
90 lb – 3/8 tsp 120 lb – 1/2 tsp
A response to the antibiotics should be seen within 7 to 10 days- -if improvement is seen during this time period, indicating that SID/SIBO is present, the antibiotics should be continued for a total 6 weeks, or at the very least a minimum of 4 weeks.
If a positive response is not seen within 7-10 days, change the antibiotic. Most EPI dogs appear to respond best to Tylosin, but if not, switch to Metronidazole (or switch from Metro to Tylan). With exceptionally difficult SI/SIBO cases, historically it has been recommended to continuously repeat or consistently continue antibiotic treatment for life. Although not clinical proven, what has been observed by diligent pet owners is that some are able to completely remove a SID/SIBO-prone dog from antibiotics through a methodical process of slowly reducing the antibiotic dose and interval while slowly introducing an increased inclusion of a safe, stable, and “agreeable” with the individual dog’s intestinal gut flora” pre and/or probiotic
Prebiotics are non-digestible food components (dietary fiber) that are being fermented by intestinal bacteria. Slippery Elm is a prebiotic. This can lead to more normalization of the intestinal microbiota. In a recent study the use of fructooligosaccharides (FOS) in the diet showed a lasting advantageous effect. This syndrome is also a potential target for probiotic therapy but one must be careful when administering probiotics. Too much FOS can cause the opposite effect. Per Dr. Jorg Steiner of Texas A&M University “…unrealistic expectations have been replaced with well-defined requirements for probiotics and controlled studies of their beneficial effects. A probiotic must be efficacious. In order to be efficacious, the bacteria must reach the intestinal lumen. This requires that the bacterial species being used in the formulation are both acid- and bile-acid resistant. Also, the bacterial species of the probiotic preparation should adhere to the intestinal mucosa to prolong the time of interaction.
When possible use a 3rd party laboratory such as http://www.consumerlab.com/ to verify product “claims”